GRACE – Excipients and Drug Delivery

Excipients and Drug Delivery

Syloid® silica excipients are the intelligent choice for many pharmaceutical applications due their unique morphology.

The combined adsorption capacity, porosity, particle size, and greater internal surface area allow it to provide several benefits simultaneously that can help minimize the number of excipients required, expedite manufacturing, and improve efficacy of the final dosage form.

Our Syloid® silica gels are widely used within the pharmaceutical industry as excipients and processing aids, and have been for many decades.  They are referenced in the United States’ FDA’s inactive ingredients database and are specifically cited in numerous drug patents due to their unique properties that improve the handling, adsorption, and dissolution of many pharmaceuticals.

Silica excipient carriers for transforming liquids to solids

SILSOLTM Silica Drug Delivery Technology combines our expertise in mesoporous silica gel, novel application methods, and patent pending technologies to accelerate the screening and development of solubility enhancing solid dispersions, with the added benefit of doing so with compendial, scalable, and available silicas. SILSOLTM Silica Drug Delivery Technology can be used with both solvent impregnation and solvent-free techniques to create amorphous solid dispersions.

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See the newest presentation of Mesoporous Silica DDS from Fred Monsuur at the 10th global DDF Summit.

 

Whitepapers / News

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Increasing Drug Solubility with Solid Dispersions of SilSol 6035 Silica Formulated Into Sublingual Tablets
AP024_Silsol Sublingual tablets_Final.pd
Adobe Acrobat Document 316.7 KB

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Mesoporous Silica Gel as a Formulation Aid for Moisture Sensitive Drugs and Excipients
PP284_water_stabilization_Tech Poster_Sy
Adobe Acrobat Document 439.8 KB

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Moisture Activated Dry Granulation (MADG) with Syloid® XDP Silica
M484_Grace_SyloidXDP_Moisure_activated_d
Adobe Acrobat Document 246.3 KB

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Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel
Worms, Germany – May 21, 2015
Worms GMT News Release 5-21-15.pdf
Adobe Acrobat Document 26.7 KB

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Grace Mesoporous Silica DDS
An Option For Liquisolid Drug Delivery Systems
Adobe Acrobat Document 2724 KB

 

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